Everyone knows the harmful effects that obesity have on your health, but what if it could be linked to breast cancer and how rapidly it spreads? A lot of research is being done to link the presence of adipose cells to breast cancer.
Two teams of researchers have been working together to make the connection between adipose cells and breast cancer. CNRS and the Universite Paul Sabatier have highlighted vitro and vivo in the presence of adipocytes around breast tumors. When located around cancerous cells they accelerate the growth of tumors.
Breast tissue is composed mainly of adipose cells, and secrete numerous proteins that may play a role in the production of breast cancer. When combined with tumor cells, the adipose cells secreted an excess of interleukin-6, which is an inflammatory protein. This leads to an increase in its "colonization potential". As well as tests performed on mice, researchers have also observed the production of IL-6 in human tumors.
"Our results now demonstrate how adipocytes actively participate in the progression of breast cancer, orchestrated by tumor cells. They suggest that in the case of obesity, the adipocytes associated with breast cancer could be more likely to amplify the 'aggressive' effect of tumors," the researchers say. "This hypothesis still needs to be verified both in mice and humans" (sciencedaily.com).
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